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US10228374B2

Antibodies with high affinity for alpha-Klotho

University of Texas Southwestern

Abstract

An antibody and/or binding fragment thereof, wherein the antibody and/or binding fragment thereof specifically binds to an epitope of a αKlotho polypeptide, optionally a folded αKiotho or optionally with a dissociation constant (K D ) of about 2 nM or less, as measured by competitive ELISA assay, …

University
University of Texas Southwestern
Assignee
Board Of Regents, The University Of Texas System
Inventor
Sachdev S. Sidhu
Priority date
July 31, 2014
Filing date
July 31, 2015
Grant date
March 12, 2019
Publication date
March 12, 2019
Language
en
Metadata fetched
August 28, 2026 19:17