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US10626087B2

Indoline and tetrahydroquinoline sulfonyl inhibitors of dimetalloenzymes and …

University of Texas System

Abstract

Indoline and tetrahydroquinoline sulfonyl compounds that can inhibit DapE and/or bacterial metallo-β-lactamases (“MBLs”), such as NDM-1 are disclosed. Also disclosed are methods of treating an individual suffering from a bacterial infection using the compounds disclosed herein.

University
University of Texas System
Assignee
Board Of Regents, The University Of Texas System
Inventor
Daniel Paul Becker
Priority date
July 10, 2015
Filing date
July 11, 2016
Grant date
April 21, 2020
Publication date
April 21, 2020
Language
en
Metadata fetched
August 29, 2026 00:27