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US10724026B2

Engineered primate L-methioninase for therapeutic purposes

University of Texas System

Abstract

Methods and compositions relating to the engineering of an improved protein with methionine-γ-lyase enzyme activity are described. For example, in certain aspects there may be disclosed a modified cystathionine-γ-lyase (CGL) comprising one or more amino acid substitutions and capable of degrading …

University
University of Texas System
Assignee
Board Of Regents, The University Of Texas System
Inventor
George Georgiou
Priority date
August 29, 2013
Filing date
February 01, 2019
Grant date
July 28, 2020
Publication date
July 28, 2020
Language
en
Metadata fetched
August 29, 2026 00:26