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US10836827B2

Antibodies specific to glycosylated PD-L1 and methods of use thereof

University of Texas System

Abstract

Antibodies that bind specifically to glycosylated PD-L1 relative to unglycosylated PD-L1 are provided. Antibodies that recognize specific epitopes of glycosylated PD-L1 protein and can block the binding of PD-L1 to PD-1 are provided. In some aspects, PD-L1 polypeptides comprising glycosylated …

University
University of Texas System
Assignee
Board Of Regents, The University Of Texas System
Inventor
Stephen S. YOO
Priority date
March 30, 2015
Filing date
March 29, 2016
Grant date
November 17, 2020
Publication date
November 17, 2020
Language
en
Metadata fetched
August 29, 2026 00:26