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US11344577B2

Car+ T cells genetically modified to eliminate expression of T-cell receptor …

University of Texas System

Abstract

The present invention concerns methods and compositions for immunotherapy employing a modified T cell comprising disrupted T cell receptor and/or HLA and comprising a chimeric antigen receptor. In certain embodiments, the compositions are employed allogeneically as universal reagents for “off-the- …

University
University of Texas System
Assignee
Board Of Regents, The University Of Texas System
Inventor
Laurence J. Neil Cooper
Priority date
November 18, 2011
Filing date
July 08, 2019
Grant date
May 31, 2022
Publication date
May 31, 2022
Language
en
Metadata fetched
August 29, 2026 00:29