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US11370786B2

GLS1 inhibitors for treating disease

University of Texas System

Abstract

Disclosed herein are compounds of structural Formula VIIa or VIIb: or a pharmaceutically acceptable salt thereof, and compositions thereof useful in the treatment of GLS1 mediated diseases, such as cancer. Methods of inhibition GLS1 activity in a human or animal subject are also provided.

University
University of Texas System
Assignee
Board Of Regents, The University Of Texas System
Inventor
Maria Emilia Di Francesco
Priority date
July 03, 2014
Filing date
July 10, 2020
Grant date
June 28, 2022
Publication date
June 28, 2022
Language
en
Metadata fetched
August 29, 2026 00:29