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US11421010B2

T cells expressing membrane-anchored IL-12 for the treatment of cancer

University of Texas System

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Abstract

Provided herein are polypeptides comprising membrane-anchored IL-12. Also provided herein are T cells expressing the membrane-anchored IL-12. Further, methods of treating cancer comprising administering T cells expressing membrane-anchored IL-12 are provided herein. Also provided are combination …

University
University of Texas System
Assignee
Board Of Regents, The University Of Texas System
Inventor
Shulin Li
Priority date
October 07, 2016
Filing date
October 06, 2017
Grant date
August 23, 2022
Publication date
August 23, 2022
Language
en
PDF source
https://patentimages.storage.googleapis.com/6d/9d/e6/e3fd8b4b62adfb/US11421010.pdf
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August 29, 2026 00:29