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US11492650B2

Production of seleno-biologics in genomically recoded organisms

University of Texas System

Abstract

Polypeptides that fold into biologies are stabilized by diselenide bonds between selenocysteine amino acids. Methods to produce such polypeptides in genomically recoded organisms (GRO) can be scaled up for industrial production. Since diselenides have the same geometric bond angles and torsions as …

University
University of Texas System
Assignee
Board Of Regents, The University Of Texas System
Inventor
Daniel J. Mandell
Priority date
August 30, 2016
Filing date
August 30, 2017
Grant date
November 08, 2022
Publication date
November 08, 2022
Language
en
Metadata fetched
August 29, 2026 00:29