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US11518800B2

Mutations that drive VH4 antibody autoreactivity

University of Texas System

Abstract

Antibodies exhibiting a specific genetically modified signature associated with certain diseases of the central nervous system, like multiple sclerosis (MS) and clinically isolated syndrome have been identified. These antibodies recognize and bind with certain tissues in the brain and central …

University
University of Texas System
Assignee
The Board Of Regents Of The University Of Texas System
Inventor
Nancy Monson
Priority date
February 01, 2016
Filing date
January 31, 2017
Grant date
December 06, 2022
Publication date
December 06, 2022
Language
en
Metadata fetched
August 29, 2026 00:29