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US11591579B2

Human methylthioadenosine/adenosine depleting enzyme variants for cancer …

University of Texas System

Abstract

Disclosed herein are compositions related to conjugated polypeptides with MTA/ADO-degrading enzyme activity. The conjugated polypeptides are engineered to allow for maximal conjugation while maintaining catalytic activities. Also disclosed are nucleic acids, expression vectors, and host cells …

University
University of Texas System
Assignee
Board Of Regents, The University Of Texas System
Inventor
Everett Stone
Priority date
January 07, 2020
Filing date
November 01, 2021
Grant date
February 28, 2023
Publication date
February 28, 2023
Language
en
Metadata fetched
August 29, 2026 00:30