US11730801B2

Live attenuated Zika virus with 3'UTR deletion, vaccine containing and use …

University of Texas System

Abstract

The present invention discloses a live attenuated strain of Zika virus (ZIKV) having a deletion in the 3′ untranslated region (3′UTR) of the viral genome, which may affect viral RNA synthesis and sensitivity to type I interferon inhibition, but may not affect viral RNA translation. The present …

University: University of Texas System
Assignee: Board Of Regents, The University Of Texas System
Inventor: Pei-Yong Shi
Priority date: February 14, 2017
Filing date: February 14, 2018
Grant date: August 22, 2023
Publication date: August 22, 2023
Language: en
PDF source: https://patentimages.storage.googleapis.com/1a/de/a1/1d7dfd599cc2a5/US11730801.pdf
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