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US12168691B2

VHS format bi-specific antibodies specific for HER2 and VEGF and use thereof

University of Texas System

Abstract

The present disclosure provides a bispecific antibody comprising an IgG linked to an scFv, wherein the VII domain of the IgG is linked to the VH domain of the scFv, the bispecific antibody binding a human vascular endothelial growth factor (VEGF) family protein and an epidermal growth factor …

University
University of Texas System
Assignee
Board Of Regents, The University Of Texas System
Inventor
Zhen Fan
Priority date
May 31, 2018
Filing date
May 31, 2019
Grant date
December 17, 2024
Publication date
December 17, 2024
Language
en
Metadata fetched
August 29, 2026 00:32