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US12251383B2

Methods and compositions for KRAS inhibitors

University of Texas System

Abstract

In one aspect, the disclosure relates to compounds that are inhibitors of KRAS, and the disclosed compounds are allosteric inhibitors of KRAS which render them extremely useful for therapeutic intervention in a variety of disorders and diseases in which inhibition of DHODH can be clinically useful …

University
University of Texas System
Assignee
The Board Of Regents Of The University Of Texas System
Inventor
Alemayehu Gorfe Abebe
Priority date
June 22, 2018
Filing date
September 08, 2021
Grant date
March 18, 2025
Publication date
March 18, 2025
Language
en
Metadata fetched
August 29, 2026 00:33