US12404296B2

Poly(A)-ClickSeq click-chemistry for next generation 3-end sequencing without …

University of Texas System

Abstract

The present invention includes a method and kit for cDNA synthesis of a 3′UTR/poly(A) tail junction of cellular RNA comprising: obtaining RNA comprising a 3′UTR/poly(A) junction and a poly(a) tail; combining the RNA with three terminating nucleotides of modified-deoxyGTP, modified-deoxyCTP and …

University: University of Texas System
Assignee: Board Of Regents, The University Of Texas System
Inventor: Andrew Routh
Priority date: February 22, 2018
Filing date: August 25, 2021
Grant date: September 02, 2025
Publication date: September 02, 2025
Language: en
PDF source: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/12404296
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