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US12441686B2

Heterocyclic g-protein-coupled receptor 52 (GPR52) agonists

University of Texas System

Abstract

Embodiments are directed to novel GPR52 activators. In particular, a series of novel 1-(pyrimidin-4-yl)indoline-4-carboxamide analogs that have been identified as potent and selective GPR52 agonists. The optimized GPR52 agonist that, for example, can be used as a valuable pharmacological tool or a …

University
University of Texas System
Assignee
Board Of Regents, The Univeristy Of Texas System
Inventor
Jia Zhou
Priority date
October 12, 2020
Filing date
August 27, 2023
Grant date
October 14, 2025
Publication date
October 14, 2025
Language
en
Metadata fetched
August 29, 2026 00:34