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US12616747B2

Stabilized beta-coronavirus antigens

University of Texas System

Abstract

Provided herein are engineered protein comprising stabilized coronavirus S protein ectodomains, such as stabilized SARS-CoV-2 S protein ectodomains. In some aspects, the engineered S protein ectodomains exhibit enhanced antigenicity. Methods are also provided for use of the engineered S protein …

University
University of Texas System
Assignee
Board Of Regents, The University Of Texas System
Inventor
Jason McLellan
Priority date
December 03, 2021
Filing date
December 02, 2022
Grant date
May 05, 2026
Publication date
May 05, 2026
Language
en
Metadata fetched
August 29, 2026 00:38