US20050069990A1

R2D2: an enzyme of RNA silencing

University of Texas System

Abstract

Methods for making siRNA comprise recombinantly coexpressing a Dicer protein with an R2D2 protein to form a complex comprising the R2D2 protein and the Dicer protein, and contacting the complex with a double-stranded (ds) RNA under conditions wherein the complex cleaves the dsRNA into siRNA. The …

University: University of Texas System
Assignee: Board Of Regents, The University Of Texas System
Inventor: Xiaodong Wang
Priority date: September 25, 2003
Filing date: September 25, 2003
Publication date: March 31, 2005
Language: en
PDF source: https://patentimages.storage.googleapis.com/9a/9a/90/f08c5c0561abda/US20050069990A1.pdf
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