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US20050197403A1

Dimeric small molecule potentiators of apoptosis

University of Texas System

Abstract

Caspase activity and apoptosis are promoted using active, dimeric Smac peptide mimetics of the general formula M1-M2, wherein moieties M1 and M2 are monomeric Smac mimetics and L is a covalent linker. Target cancerous or inflammatory cells are contacted with an effective amount of an active, …

University
University of Texas System
Assignee
Board Of Regents, The University Of Texas System
Inventor
Patrick Harran
Priority date
March 01, 2004
Filing date
March 01, 2005
Publication date
September 08, 2005
Language
en
Metadata fetched
August 28, 2026 23:57