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US20050239134A1

Combinatorial selection of phosphorothioate single-stranded DNA aptamers for …

University of Texas System

Abstract

The present invention includes the selection and isolation of thioaptamers that target the signaling protein TGF-β1, compositions of such thioaptamers and the use of such thioaptamers to either block or enhance signal transduction of the TGF-β1 protein and thus function as, e.g., immunomodulatory …

University
University of Texas System
Assignee
Board Of Regents, The University Of Texas System
Inventor
David Gorenstein
Priority date
April 21, 2004
Filing date
April 21, 2004
Publication date
October 27, 2005
Language
en
Metadata fetched
August 28, 2026 23:57