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US20060051829A1

Regulating PAS domain function with foreign PAS ligands

University of Texas System

Abstract

A functional surface binding specificity of a PAS domain, wherein the PAS domain is predetermined, prefolded in its native state, and comprises a hydrophobic core that has no NMR-apparent a priori formed ligand cavity, is changed by (a) introducing into the hydrophobic core of the PAS domain a …

University
University of Texas System
Assignee
Board Of Regents, The University Of Texas System
Inventor
Kevin Gardner
Priority date
January 26, 2001
Filing date
October 11, 2005
Publication date
March 09, 2006
Language
en
Metadata fetched
August 29, 2026 00:17