US20060228299A1

Constructs binding to phosphatidylserine and their use in disease treatment

University of Texas System

Abstract

1 . A construct comprising an antibody Fc region operatively attached to two β2-glycoprotein I (β2GPI) polypeptides, wherein said β2GPI polypeptides each comprise at least domain V of β2GPI and wherein said β2GPI polypeptides form a dimer when attached to said Fc region. 2 . The construct of claim 1

University: University of Texas System
Assignee: Board Of Regents, The University Of Texas System
Inventor: Philip Thorpe
Priority date: January 24, 2005
Filing date: January 24, 2006
Publication date: October 12, 2006
Language: en
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