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US20080286286A1

Methods to Treat Disease States by Influencing the Signaling of Ox-40-Receptors …

University of Texas System

Abstract

OX40L inhibits the generation of IL-10-producing Tr1 cells from naïve and memory CD4+ T cells induced by the immunuosuppressive drugs dexamethasone and vitamin D3. This unique function of OX40L is not shared by two other costimulatory TNF-family members, GITR-ligand and 4-1BB-ligand. OX40L also …

University
University of Texas System
Assignee
Board Of Regents, The University Of Texas System
Inventor
Yong-Jun Liu
Priority date
January 13, 2006
Filing date
January 16, 2007
Publication date
November 20, 2008
Language
en
Metadata fetched
August 29, 2026 00:18