US20100189725A1

P53 modulator and cancer target

University of Texas System

Abstract

Methods of screening for modulators of TRIM24 (also known as TIF1-ALPHA) expression and/or biological activity are described. In particular, methods of screening of screening for modulators of TRIM24 E3 ligase activity, and specifically an E3 ligase activity directed at p53 as the target …

University: University of Texas System
Assignee: Board Of Regents, The University Of Texas System
Inventor: Michelle Barton
Priority date: July 03, 2007
Filing date: July 03, 2008
Publication date: July 29, 2010
Language: en
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