US20120135408A1

Unc-45a splice variants based cancer diagnostics and therapeutics

University of Texas System

Abstract

Methods and compositions to diagnose and treat cancers using UNC-45A splice variants are disclosed. Expression of a human UNC-45A929 splice variant that is shorter than UNC-45A944 splice variant is increased in cancer cells including metastatic cancers. siRNA to inhibit or downregulate UNC-45A …

University: University of Texas System
Assignee: The Board Of Regents Of The University Of Texas System
Inventor: Henry Fredric Epstein
Priority date: January 13, 2009
Filing date: January 12, 2010
Publication date: May 31, 2012
Language: en
PDF source: https://patentimages.storage.googleapis.com/8e/56/72/125d32c47d2501/US20120135408A1.pdf
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