US20130143227A1
University of Texas System
A composition and method for detecting the ability of a compound to modulate the activity of LGR4, LGR5, or LGR6 receptors in a cell. LGR4, LGR5, and LGR6 are capable of activating the Wnt/β-catenin signaling system which plays essential roles in embryonic development and in the self-renewal and …