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US20130331426A1

pH-SENSITIVE COMPOSITIONS FOR DELIVERY OF BETA LAPACHONE AND METHODS OF USE

University of Texas System

Abstract

1 . A compound comprising a polymer conjugated with a pH-sensitive prodrug of beta-lapachone, wherein the compound is capable of forming a micelle, and wherein the pH-sensitive prodrug comprises a pH-sensitive linker selected from the group consisting of: an aryl imine and an aliphatic imine. 2 .

University
University of Texas System
Assignee
The Board Of Regents Of The University Of Texas System
Inventor
Jinming Gao
Priority date
September 22, 2010
Filing date
August 11, 2011
Publication date
December 12, 2013
Language
en
Metadata fetched
August 29, 2026 00:21