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US20170130198A1

Mitochondrial inhibitors for use in culturing pluripotent stem cells

University of Texas System

Abstract

Disclosed are certain heterocyclic organic compounds that inhibit mitochondrial respiration and also lead to the maintenance of pluripotency of human embryonic stem cells in culture, even in the presence of oxygen. Exemplified are compounds, such as substituted 5-aminotetrazoles, which are …

University
University of Texas System
Assignee
Board Of Regents Of The University Of Texas System
Inventor
David Alvin Tyvoll
Priority date
June 20, 2014
Filing date
June 19, 2015
Publication date
May 11, 2017
Language
en
Metadata fetched
August 29, 2026 00:25