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US20170166624A1

TGFß TYPE II-TYPE III RECEPTOR FUSIONS

University of Texas System

Abstract

Certain embodiments are directed to TGF-β inhibitors EUc and REUc. EUc is generated by removing the non-binding N-terminal subdomain from the TGF-β type III receptor, and REUc is generated by fusing together the binding domains of the TGF-β type II (RII or R) and type III receptor (RIII or EU) by …

University
University of Texas System
Assignee
The Board Of Regents Of The University Of Texas System
Inventor
Andrew Hinck
Priority date
July 14, 2014
Filing date
July 14, 2015
Publication date
June 15, 2017
Language
en
Metadata fetched
August 29, 2026 00:25