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US20180008681A1

Human-enzyme mediated depletion of cystine for treating patients with …

University of Texas System

Abstract

Methods and compositions related to the engineering of a protein with L-cyst(e)ine degrading enzyme activity are described. For example, in certain aspects there may be disclosed a modified cystathionine-γ-lyase comprising one or more amino acid substitutions and capable of degrading L-cyst(e)ine.

University
University of Texas System
Assignee
Board Of Regents, The University Of Texas System
Inventor
Everett Stone
Priority date
July 06, 2016
Filing date
July 06, 2017
Publication date
January 11, 2018
Language
en
Metadata fetched
August 29, 2026 00:26