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US20180251454A1

Dna binding agents with a minor groove binding tail

University of Texas System

Abstract

Provided herein are compounds which intercalate into the DNA of a cell and are capable of crossing the blood brain barrier of a formula provided herein. Pharmaceutical compositions of the compounds and methods of treating cancer, for example brain, lung, or pancreatic cancer, are also provided …

University
University of Texas System
Assignee
Board Of Regents, The University Of Texas System
Inventor
Waldemar Priebe
Priority date
September 16, 2015
Filing date
September 16, 2016
Publication date
September 06, 2018
Language
en
Metadata fetched
August 29, 2026 00:26