US20180353476A1
Southern Methodist University
The present invention includes a composition, method of making and method of using a novel C5-substituted carbapenem antibiotic of formula 1: R 1 is H or CH 3 R 2 is not H, and is CH 3 , or C1-C6 straight chain, or branched alkyl, or C3-C6 cycloalkyl group, or unsaturated alkenyl, including C═CH 2 ; R 3 …