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US20190330593A1

Lilrb2 and notch-mediated expansion of hematopoietic precursor cells

University of Texas Southwestern

Abstract

The current disclosure describes methods of expanding precursor cells for hematopoietic transplantation in subjects. The methods culture precursor cells in media containing an immobilized high molecular weight LILRB2 agonist or an LILRB2 agonist in combination with a Notch agonist. The expanded …

University
University of Texas Southwestern
Assignee
Board Of Regents Of The University Of Texas System
Inventor
Irwin D. Bernstein
Priority date
May 22, 2014
Filing date
June 26, 2019
Publication date
October 31, 2019
Language
en
Metadata fetched
August 28, 2026 19:16