US20200032209A1

Enhanced Expansion of Tumor-Infiltrating Lymphocytes for Adoptive Cell Therapy

University of Texas System

Abstract

Disclosed herein is a method for ex vivo expanding tumor-infiltrating lymphocytes for use in adoptive cell therapy (ACT). The method involves culturing tumor fragments from the subject in a culture medium containing IL-2 and a 41BB agonist in an amount effective to expand tumor-infiltrating …

University: University of Texas System
Assignee: Board Of Regents, The University Of Texas System
Inventor: Amod A. Sarnaik
Priority date: April 10, 2014
Filing date: December 20, 2018
Publication date: January 30, 2020
Language: en
PDF source: https://patentimages.storage.googleapis.com/57/19/8a/9377842f6c85e9/US20200032209A1.pdf
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