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US20200164034A1

Methods for improving sex-dimorphic responses to targeted therapy in melanoma

University of Texas System

Abstract

Provided herein are methods for the treatment of BRAF-mutant cancer with targeted therapies including androgen receptor (AR) antagonists, G Protein-Coupled Estrogen Receptor 1 (GPER1) agonists, and/or MYC inhibitors. The therapies may be combined with BRAF and MEK-targeted therapy and/or immune …

University
University of Texas System
Assignee
Board Of Regents, The University Of Texas System
Inventor
Jennifer WARGO
Priority date
October 24, 2018
Filing date
October 24, 2019
Publication date
May 28, 2020
Language
en
Metadata fetched
August 29, 2026 00:27