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US20200181201A1

Targeting alpha2delta-1-bound glutamate receptors for treating diseases and …

University of Texas System

Abstract

The present disclosure provides α2δ-1 C-terminal domain mimetics for the treatment of pain, epilepsy or other disorders in a subject. Further provided is an α2δ-1 C-terminal domain peptide which blocks binding of α2δ-1 to the glutamate receptors NMDAR and AMPAR.

University
University of Texas System
Assignee
Board Of Regents, The University Of Texas System
Inventor
Hui-lin PAN
Priority date
August 14, 2017
Filing date
August 14, 2018
Publication date
June 11, 2020
Language
en
Metadata fetched
August 29, 2026 00:27