Enzyme-mediated depletion of adenosine and/or methylthioadenosine

Abstract

What is claimed is: 1 . A composition for treating a methylthioadenosine phosphorylase-deficient cancer comprising: an enzyme capable of phosphorolysis of methylthioadenosine into methylthioribose-phosphate and adenine coupled to a compound capable of increasing a serum half-life of the enzyme. 2 .