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US20210115024A1

Small molecule inducers of autophagy

University of Texas System

Abstract

Small molecule disruptors of Beclin-1/Bcl-2 protein-protein interactions induce autophagy and hence are useful for treating a variety of indications where stimulation of autophagy is therapeutically useful, including cancer, infection immunity, neurodegeneration, longevity.

University
University of Texas System
Assignee
Board Of Regents, The University Of Texas System
Inventor
Jef De Brabander
Priority date
June 04, 2018
Filing date
December 04, 2020
Publication date
April 22, 2021
Language
en
Metadata fetched
August 29, 2026 00:28