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US20210260051A1

Combination of ezh2 inhibitor and checkpoint therapy for the treatment of …

University of Texas System

Abstract

Provided herein are methods of treating cancer comprising administering an EZH2 inhibitor which may be combined with an immune checkpoint inhibitor. Further provided herein are methods of depleting regulatory T cells (Tregs) in a subject comprising administering an EZH2 inhibitor to the subject.

University
University of Texas System
Assignee
Board Of Regents, The University Of Texas System
Inventor
Padmanee Sharma
Priority date
June 14, 2018
Filing date
June 14, 2019
Publication date
August 26, 2021
Language
en
Metadata fetched
August 29, 2026 00:28