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US20220016205A1

Methods of overcoming resistance to immune checkpoint inhibitors

University of Texas System

Abstract

Provided herein are methods of using BMP7 levels as a marker for the selection of patients, such as non-small cell lung cancer patients, who will clinically respond to combination therapy comprising a BMP7 inhibitor and an immune checkpoint therapy, such as an anti-PD1 therapy and/or an anti-CTLA- …

University
University of Texas System
Assignee
Board Of Regents, The University Of Texas System
Inventor
James Welsh
Priority date
November 21, 2018
Filing date
November 21, 2019
Publication date
January 20, 2022
Language
en
Metadata fetched
August 29, 2026 00:30