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US20220031749A1

Multiplex genome editing of immune cells to enhance functionality and …

University of Texas System

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Abstract

Provided herein are methods for producing immune cells with disruption of multiple genes. Further provided are methods for inserting a chimeric antigen receptor at a gene locus of an immune cell.

University
University of Texas System
Assignee
Board Of Regents, The University Of Texas System
Inventor
Rafet Basar
Priority date
November 28, 2018
Filing date
November 27, 2019
Publication date
February 03, 2022
Language
en
PDF source
https://patentimages.storage.googleapis.com/2a/3f/17/4138f600a3b6b6/US20220031749A1.pdf
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