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US20220144926A1

Identification and targeting of pathogenic extracellular matrix for diagnosis …

University of Texas System

Abstract

Provided herein are agents, such as antibodies or chimeric antigen receptors, that target homotrimeric type I collagen. Methods of treating cancer and fibroids are provided, comprising administering to a patient in need thereof an effective amount of a homotrimeric type I collagen-neutralizing …

University
University of Texas System
Assignee
Board Of Regents, The University Of Texas System
Inventor
Raghu Kalluri
Priority date
October 16, 2018
Filing date
October 16, 2019
Publication date
May 12, 2022
Language
en
Metadata fetched
August 29, 2026 00:29