US20220202858A1

Methods and compositions for modification of hla

University of Texas System

Abstract

Disclosed herein are methods and compositions for modulating the expression of a HLA locus, including Natural Killer (NK) cells that lack expression of one or more classic HLA genes and comprise one or more exogenous sequences that express one or more non-classic HLA gene.

University: University of Texas System
Assignee: Board Of Regents, The University Of Texas System
Inventor: Philip D. Gregory
Priority date: March 12, 2013
Filing date: July 22, 2021
Publication date: June 30, 2022
Language: en
PDF source: https://patentimages.storage.googleapis.com/52/2a/82/6d8d8d11e24926/US20220202858A1.pdf
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