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US20220409711A1

Hla restricted hormad1 t cell receptors and uses thereof

University of Texas System

Abstract

Provided are T cell receptors (TCR) and TCR variable regions that can selectively bind a Hormad1 peptide/MHC complex. The TCR may be utilized in various therapies, such as autologous Hormad1-TCR adoptive T cell therapy to treat a cancer, such as a solid tumor expressing Hormad1. Methods for …

University
University of Texas System
Assignee
Board Of Regents, The University Of Texas System
Inventor
Cassian Yee
Priority date
November 05, 2019
Filing date
November 05, 2020
Publication date
December 29, 2022
Language
en
Metadata fetched
August 29, 2026 00:29