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US20240009223A1

6-thio-2'-deoxyguanosine (6-thio-dg) results in telomerase dependent telomere …

University of Texas System

Abstract

The present disclosure provide for methods of using 6-thio-2′-deoxyguanosine (6-thio-dG) to treat telomerase-positive cancers that exhibit (a) one or more TERT promoter mutations, and/or (b) enriched telomere transcriptional signature(s). In particular, melanomas, including those who are not …

University
University of Texas System
Assignee
The Board Of Regents Of The University Of Texas System
Inventor
Jerry W. Shay
Priority date
May 27, 2016
Filing date
June 05, 2023
Publication date
January 11, 2024
Language
en
Metadata fetched
August 29, 2026 00:31