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US20240148757A1

Use of dihydroorotate dehydrogenase (dhodh) inhibitors to target ferroptosis in …

University of Texas System

Abstract

The present disclosure provides methods for treating cancer comprising administering to a subject in need thereof a therapeutically effective amount of a dihydroorotate dehydrogenase (DHODH) inhibitor, wherein the cancer has an altered glutathione peroxidase 4 (GPX4) expression as compared to a …

University
University of Texas System
Assignee
Board Of Regents, The University Of Texas System
Inventor
Boyi GAN
Priority date
March 03, 2021
Filing date
March 03, 2022
Publication date
May 09, 2024
Language
en
Metadata fetched
August 29, 2026 00:32