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US20240317810A1

Prefusion-stabilized chimeric hmpv-rsv f proteins

University of Texas System

Abstract

Provided herein are chimeric hMPV/RSV F proteins. In some aspects, the chimeric hMPV/RSV F proteins exhibit enhanced conformational stability, enhanced thermostability, and/or increased expression. Methods are also provided for use of the chimeric F proteins as diagnostics, in screening platforms, …

University
University of Texas System
Assignee
Board Of Regents, The University Of Texas System
Inventor
Jason McLellan
Priority date
July 15, 2021
Filing date
July 15, 2022
Publication date
September 26, 2024
Language
en
Metadata fetched
August 29, 2026 00:31