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US20240325444A1

Chimeric antigen receptor to target trop-2-positive cancers

University of Texas System

Abstract

Embodiments of the disclosure include methods and compositions related to targeting of TROP-2-expressing cells with particular engineered receptors. In specific embodiments, NK cells are specifically engineered to bind TROP-2 using particular chimeric antigen receptor constructs. In certain …

University
University of Texas System
Assignee
Board Of Regents, The University Of Texas System
Inventor
Katy REZVANI
Priority date
July 09, 2021
Filing date
July 08, 2022
Publication date
October 03, 2024
Language
en
Metadata fetched
August 29, 2026 00:31