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US20240424013A1

SEQUENTIAL TREATMENT OF CANCERS USING 6-THIO-dG, CHECKPOINT INHIBITORS AND …

University of Texas Southwestern

Abstract

Disclosed herein are methods of treatments with a telomerase-mediated telomere-targeting drug, 6-thio-2′-deoxyguanosine (6-thio-dG), checkpoint inhibitors and/or radiation therapy for treating cancers. eads to tumor regression in innate and adaptive immune-dependent manners in syngeneic and …

University
University of Texas Southwestern
Assignee
The Board Of Regents Of The University Of Texas System
Inventor
Jerry Shay
Priority date
March 13, 2020
Filing date
September 09, 2024
Publication date
December 26, 2024
Language
en
Metadata fetched
August 28, 2026 19:16