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US20250019465A1

Compositions and methods for rare heparan sulfate glycan-targeted cancer …

University of Texas System

Abstract

Provided herein are single domain antibodies (sdAbs) having a specific affinity for a rare heparan sulfate moiety which can be used to disrupt DC-HIL function to reduce and prevent cancer progression and metastasis. Compositions and methods of use thereof are also provided for use of these sdAbs …

University
University of Texas System
Assignee
The Board Of Regents Of The University Of Texas System
Inventor
Kiyoshi Ariizumi
Priority date
November 12, 2021
Filing date
November 14, 2022
Publication date
January 16, 2025
Language
en
Metadata fetched
August 29, 2026 00:35