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US20250049809A1

Inhibitors of mutant idh1 and idh2

University of Texas System

Abstract

Disclosed herein are compounds, and salts thereof, which inhibit mutant IDH proteins. Also disclosed are pharmaceutical formulations and methods of treatment for diseases associated with an IDH protein having one or more neomorphic mutations, such as certain cancers.

University
University of Texas System
Assignee
Board Of Regents, The University Of Texas System
Inventor
Fernando G. ALVAREZ
Priority date
July 31, 2023
Filing date
July 29, 2024
Publication date
February 13, 2025
Language
en
Metadata fetched
August 29, 2026 00:36